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Individuals experiencing depression will often be recommended an antidepressant.

But while the unwanted side effects of the prescriptions (weight gain, headaches, etc.) are widely recognized, one effect is just just starting to be discussed publicly. They may stop working.

If you find that your medication isn’t effective anymore, and your depression symptoms are resurfacing, there are various reasons why this might be occurring.


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For most people with depression, a definitive depression diagnosis from a psychiatrist often means accepting that you will be on antidepressants for most of your life. For many, this means delaying the first prescription for as long as possible, but after some time, the use of the antidepressants is inevitable. Unfortunately, from the time you accept medication, even as your symptoms lift, another heavy cloud hovers – the fact that the medications you now depend on come with adverse side effects. And, you might never get over the effects of the medication even though


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Antidepressants balance chemicals within brain that control depression and anxiety. For some with depression, these drugs can easily improve a chemical imbalance.

Anyone who has used antidepressants for more than six-weeks are more inclined to have withdrawal symptoms once they halt the drugs.

Individuals taking antidepressants should not quit “cold turkey.” Stopping abruptly tosses the brain into a situation of imbalance that may be more serious than earlier. The resulting problems are generally psychological and physical.


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In 2008, the FDA approved Cymbalta for the treatment of fibromyalgia, and the drug was effectively classified as a serotonin-norepinephrine reuptake inhibitor antidepressant. This was good news for the fibromyalgia (FM) community as before this approval, there was only one other drug accessible for the treatment of FM.

While Cymbalta was great news, it was/is an antidepressant at the end of the day, and so the medical fraternity was already aware of potential withdrawal symptoms if patients abruptly stopped using it. Still, no one was ready for the severe Cymbalta withdrawal that is experienced by patients. It is so bad that the medical fraternity has coined a term for it: Cymbalta Discontinuation Syndrome.


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Through Plasticity we will overcome. Despite what we knew in the past, our brains are easily shaped and ever-changing. We strive to take advantage of this adaptability with supplements in order to overcome the withdrawal effects of antidepressants.

Copyright by NfiniteLimits 2019. All rights reserved.

Before proceeding, please indicate that you have read and understand the following:

The process of reducing or tapering off psychiatric medication is inherently risky and can be especially dangerous and potentially life-threatening if done faster than one’s body can handle. Cymbalta-Withdrawal’s website sets forth information which relates to this process. Cybmalta-Widthrawal shares such information on website for the sole purpose of making it available for general educational purposes to those who are interested in it. The information does not constitute Cymbalta Withdrawal’s advice, encouragement, or recommendation that any individual reduce or taper off of his or her intake of psychiatric medication.

Unless expressly stated otherwise, Cymbalta Withdrawal’s authors, bloggers, and/or editors of Cymbalta Withdrawal Project website are laypeople who have direct personal experience or who have supported someone else in the process of reducing or tapering off psychiatric medication. The information shared neither constitutes nor should be interpreted as the professional medical advice of a physician, pharmacist, or other prescriber of psychiatric medication.

Please check out our medical disclaimer page, here.

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